Coordination polymers nanoparticles for bioimaging

Early diagnosis of patient diseases is subjected to the appropriate use bioimaging techniques. For this reason, development contrast agents that improve and enhance response current clinical imaging practices a pressing concern. Non-invasive techniques most often need specific probes follow measure biological routes in living systems. These molecular must exhibit: I) remarkable effect, i.e. high signal-to-noise ratio under real physiological conditions, II) pronounced vivo stability effect numerous enzymes or proteases present serum targeted tissue equilibrated with fast clearance from healthy organs III) low cost eco-friendly production. To overcome drawbacks hindrance full different techniques, several groups are exploring nanoparticles as agents. In scenario, coordination polymer have emerged handy platform offering predesigned unique advantages thanks their chemical flexibility, structural diversity tailoring skills. Indeed, these systems reveal metal cargos, toxicity multifunctional character by adequately selecting combination ions ligands. Moreover, reminiscent way organic polymeric nanoparticles, also demonstrated its ability encapsulate therapeutic-active molecules, thus combining diagnostic therapeutic functionalities, so-called Theranostic nanomedicine. all reasons, family has attracted broad interest over last years examples being reported. Herein, we review main accomplishments area grouped according used technology, including magnetic resonance imaging, computed tomography, optical radioimaging photoacoustic imaging.